1
general::
Unable to cope with or manage someone or something. For example, I can't do anything with my hair, or My teenage daughter is very difficult? I can't do anything with her. This expression uses do in the sense of "deal with," a usage dating from the early 1500s.
American Heritage Idioms
2
general::
Phrase(s): can’t do anything with someone or something
not [to be] able to manage or control someone or something. (Also with cannot.) • Bill is such a discipline problem. I can’t do anything with him. • My hair is such a mess. I just can’t do anything with it.
McGrawhill's American Idioms And Phrasal Verbs